Endocrine Abstracts

Prolactin-secreting (PRL) adenomas are about 40% of all pituitary adenomas. The most important clinical symptoms of PRL excess are gonadal and sexual dysfunction as a result of tumor expansion in patients with macroadenomas. Medical therapy of prolactinomas relies on the use of dopamine agonists which induce normalization of PRL levels and shrinkage of the tumor mass in the majority of patients. The present study evaluated whether doses of dopamine agonist inducing normalizati...

Introduction: AIT develops in 15–20% of patients receiving amiodarone. Patients with persistent thyrotoxicosis or those with instable cardiac function, may be candidate for thyroidectomy; however, thyrotoxicosis and underlying cardiovascular disease may increased surgical risk.Matherials and methods: We retrospectively selected 23 AIT patients treated with a total thyroidectomy, from January 2000 to December 2010 [19 men, 4 women; mean (+SD), age 61...